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</topic><topic id="https://vocabulario.abcd.usp.br/pt-br/?tema=95892"><instanceOf><topicRef xlink:href="#term"/></instanceOf><baseName><baseNameString>TOLERÂNCIA IMUNOLÓGICA</baseNameString></baseName>  <occurrence>    <instanceOf>      <topicRef xlink:href="#scope-note"/>    </instanceOf><baseName><baseNameString><![CDATA[ Insuficiência específica de um indivíduo normalmente responsivo para produzir uma resposta imune a um antígeno conhecido. Resulta de um contato prévio com o antígeno por um indivíduo imunologicamente imaturo (feto ou neonato) ou por um adulto exposto a uma dose de antígeno extremamente elevada ou baixa, ou ainda por exposição à radiação, antimetabólitos, soro antilinfocítico, etc.<p>Fonte: DeCS. Disponível em: https://decs.bvsalud.org<p> ]]></baseNameString></baseName>  </occurrence></topic>  <association>    <instanceOf>      <topicRef xlink:href="#broader-narrower"/>    </instanceOf>    <member>      <roleSpec>  <topicRef xlink:href="#narrower"/>      </roleSpec>      <topicRef xlink:href="#https://vocabulario.abcd.usp.br/pt-br/?tema=95892"/>    </member>    <member>      <roleSpec>  <topicRef xlink:href="#broader"/>      </roleSpec>      <topicRef xlink:href="#https://vocabulario.abcd.usp.br/pt-br/?tema=52224"/>    </member>  </association></topicMap>